FOXO3, SIRT1, KLOTHO, TERT, and OBFC1 variants are the genomic context for longevity science. Hyman translates the lab science into actionable lifestyle protocols.
Hyman applies longevity science — autophagy, senescent cells, epigenetic aging clocks — to a practical program of diet, fasting, exercise, and supplementation, framing aging itself as a treatable condition.
Hyman's most comprehensive longevity synthesis.
These peer-reviewed studies connect to the core ideas in this book. Each result has been scored for reliability.
The most accessible book specifically on MTHFR and the methylation cycle. Covers folate forms, homocysteine, and the B vitamin cofactors your body needs when the MTHFR enzyme runs at reduced efficiency.
Dr. Panda leads one of the world's top labs on time-restricted eating and circadian biology. His research on meal timing and metabolic health maps directly to what peer-reviewed studies have found for MTNR1B GG carriers — making when you eat as important as what you eat.
Covers the research on how specific nutrients — omega-3s, B vitamins, fat-soluble vitamins — affect brain and metabolic function. Directly relevant to FADS1 and BCMO1 variant research on nutrient conversion efficiency.