Directly relevant to TCF7L2 TT, MTNR1B GG, KCNJ11, and LEPR variants — all of which affect glucose metabolism. Lustig explains the mechanisms behind why these variants create elevated metabolic risk in an environment saturated with added sugar.
Lustig, a pediatric endocrinologist at UCSF, argues that fructose drives insulin resistance and metabolic disease independent of calorie count — making sugar a metabolic toxin at population-level doses, particularly for children. Built on his viral 'Sugar: The Bitter Truth' lecture and years of clinical research in pediatric obesity.
The book that translated Lustig's viral 'Sugar: The Bitter Truth' lecture into a full clinical case against added fructose.
These peer-reviewed studies connect to the core ideas in this book. Each result has been scored for reliability.
The most accessible book specifically on MTHFR and the methylation cycle. Covers folate forms, homocysteine, and the B vitamin cofactors your body needs when the MTHFR enzyme runs at reduced efficiency.
Dr. Panda leads one of the world's top labs on time-restricted eating and circadian biology. His research on meal timing and metabolic health maps directly to what peer-reviewed studies have found for MTNR1B GG carriers — making when you eat as important as what you eat.
Covers the research on how specific nutrients — omega-3s, B vitamins, fat-soluble vitamins — affect brain and metabolic function. Directly relevant to FADS1 and BCMO1 variant research on nutrient conversion efficiency.