APOE e3/e3 (or e3/e4), FOXO3, BDNF, SIRT1, and inflammatory variant carriers have specific Alzheimer's risk context that Bredesen's framework addresses. The personalized, root-cause approach aligns with genomic thinking even if the specific protocol is contested.
A neurologist specializing in neurodegenerative disease proposes that Alzheimer's is not one disease but multiple subtypes driven by different combinations of inflammation, nutrient deficiency, and toxin exposure — and proposes a personalized multi-factor ReCODE protocol.
The most-cited proponent of the personalized, multi-factor approach to preventing Alzheimer’s.
These peer-reviewed studies connect to the core ideas in this book. Each result has been scored for reliability.
The former director of the Human Genome Project explains what your DNA actually tells you and what it does not. The most credible plain-language introduction to personal genomics available — written for a general audience without overselling what genetics can predict.
Two social scientists with genomics expertise give an honest, rigorous account of what polygenic scores and genetic associations actually mean for individuals versus populations. Essential reading for anyone who wants to understand the real limits of genetic prediction.
The co-inventor of CRISPR explains how gene editing works and what it means for medicine and humanity. Provides essential context for where genomics is heading and why understanding your current genome matters now.